Hubungan Riwayat Reproduksi dengan Tumor Payudara pada Perempuan Usia Muda di Indonesia (Analisis Riset PTM 2016)
Abstract
The incidence of breast tumor increases every year in Indonesia. At present, breast tumors do not onlyattack the elderly, but also at young age. Some studies show factors associated with breast tumors. Therefore,this study aimed to study the association of the reproductive history with tumor incidence in young women inIndonesia in 2016. This study used a cross-sectional study design and was conducted in December 2018-January2019 in the Faculty of Public Health of Universitas Indonesia using secondary data from the Riset PTM 2016(Non-communicable Disease Research 2016). The population in this study were all respondents of the 2016 PTMResearch. The sample was 14,891 respondents (total sampling) aged under 40 years who meet the inclusion andexclusion criteria. The variables used in this study were independent variables consisting of age of menarche, ageof first birth, marital status, breasfeeding history, the use of hormonal contraception; and the dependent variableis the incidence of breast tumors. The data was analyzed by chi square and logistic regression test. The resultsshowed an association between menarche age (OR=1,269), marital status (OR=1,353), breasteeding history(OR=1,295), and the use of hormonal contraception more than 5 years (OR=1,113) with breast tumors in youngwomen in Indonesia.
References
1. Riley T. Benign Breast Disease. Physician Assistant Clinics. 2018:3(3);363–371.
2. Sharma GN, Dave R, Sanadya J, Shama P, Sharma KK. Various Types and Management of Breast Cancer: An Overview. Journal of Advanced Pharmaceutical Technology & Research. 2010:1(2);109–126.
3. WHO. Guidelines for Management of Breast Cancer. Regional Office for the Eastern Mediterranean. WHO; 2006.
4. Anyikam A, Nzegwu MA, Ozumba BC, Okoye I, Olusina DB. Benign Breast Lesions in Eastern Nigeria. Saudi Medical Journal. 2008:29(2);241-244.
5. Kotepui M, Piwkham D, Chupeerach C, Songsri A, Charoenkijkajorn L. Epidemiology and Histopathology of Benign Breast Diseases and Breast Cancer in Southern Thailand. European Journal of Gyneacological Oncology. 2014:35(6);670-675.
6. Kementerian Kesehatan RI. Data Program Deteksi Dini Sadanis dan IVA. Jakarta: Kementerian Kesehatan: Subdit Penyakit Kanker dan Kelainan Darah; 2018.
7. Cardoso, Loibl, Pagani, Graziottin, Panizza, Martincich, et al. The European Society ofBreast Cancer Specialists Recommendations for the Management of Young Women with Breast Cancer. European Journal of Cancer.2012:48(2);3355-3377.
8. Azim HJ, Partridge A. Biology of Breast Cancer in Young Women. Breast Cancer Research. 2014:16(4);1-9.
9. Kementerian Kesehatan RI. Laporan Riset Penyakit Tidak Menular: Tumor Payudara dan Lesi Prakanker Serviks. Jakarta: Badan Penelitian dan Pengembangan Kesehatan;2016.
10. Castells X, Domingo L, Corominas J, Torá-Rocamora I, Quintana M, Baré M, et al. Breast Cancer Risk After Diagnosis by Screening Mammography of Nonproliferative or Proliferative Benign Breast Disease: A Study from A Population-based Screening Program. Breast Cancer Research and Treatment. 2015:149(1);237-244.
11. Murti B. Prinsip dan Metode Riset Epidemiologi. Yogyakarta: UGM; 1997.
12. Dewi GAT, Hendrati LY. Analisis Risiko Kanker Payudara Berdasar Riwayat Pemakaian Kontrasepsi Hormonal dan Usia Menarche. Jurnal Berkala Epidemiologi. 2015:3(1);12-23.
13. Nasution WM, Asfriyanti. The Analysis of Breast Cancer Causes at General Hospital Dr. Pringadi Medan. Advances in Health Sciences Research. 2017:9(2);43-47.
14. Bidgoli S, Eftekhari T. Role of Exogenous and Endogenous Sources of Estrogen on the Incidence of Breast Fibroadenoma: Casecontrol Study in Iran. Asian Pacific Journal Cancer Prevention. 2011:12(5);1289-1293.
15. Lambe M, Hsieh C, Trichopoulos D, Ekbom A, Pavia M, Adami H. Transient Increase in the Risk of Breast Cancer after Giving Birth. New England Journal of Medicine. 1994:331(1);5-9.
16. Sihombing M, Sapardin A. Faktor Risiko Tumor Payudara pada Perempuan Umur 25-65 Tahun di Lima Kelurahan Kecamatan Bogor Tengah. Indonesian Journal of Reproductive Health. 2014:5(3);175-184.
17. American Cancer Society. Breast Cancer Facts & Figure 2013-2014. Atlanta: American Cancer Society; 2014.
18. Anggraini M. Hubungan Antara Usia Saat Timbulnya Menarche dengan Usia Saat Terjadinya Menopause Wanita di Kecamatan Kartasura. Jurnal Unimus. 2008:5(1);203-209.
19. Pratiwi H, Sety L, Tina L. Analisis Faktor Risiko Kejadian Penyakit Fibroadenoma Mammae (FAM) di Rumah Sakit Umum Daerah Bahteramas Provinsi Sulawesi Tenggara Tahun 2017. Jurnal Ilmiah Mahasiswa Kesehatan Masyarakat. 2017:3(2);2-11.
20. Hinyard L, Schwartz T. Marital Status, Stage of Diagnosis, and Survival in Younger Women with Breast Cancer. Value in Health Journal. 2016:19(3): A169.
21. Kvikstad A, Vatten LJ. Cancer Risk and Prognosis in Norway: Comparing Women in Their First Marriage with Women Who Have Never Married. Journal of Epidemiology and Community Health. 1996:50(1);51-55.
22. Rianti E, Tirtawati GA, Novita H. Faktor-Faktor yang Berhubungan dengan Risiko Kanker Payudara Wanita. Journal Health Quality. 2012:3(1);10-23.
23. Russo J, Russo I. Breast Development, Hormones, and Cancer. Advances in Experimental Medicine and Biology. 2008:630;52-56.
2. Sharma GN, Dave R, Sanadya J, Shama P, Sharma KK. Various Types and Management of Breast Cancer: An Overview. Journal of Advanced Pharmaceutical Technology & Research. 2010:1(2);109–126.
3. WHO. Guidelines for Management of Breast Cancer. Regional Office for the Eastern Mediterranean. WHO; 2006.
4. Anyikam A, Nzegwu MA, Ozumba BC, Okoye I, Olusina DB. Benign Breast Lesions in Eastern Nigeria. Saudi Medical Journal. 2008:29(2);241-244.
5. Kotepui M, Piwkham D, Chupeerach C, Songsri A, Charoenkijkajorn L. Epidemiology and Histopathology of Benign Breast Diseases and Breast Cancer in Southern Thailand. European Journal of Gyneacological Oncology. 2014:35(6);670-675.
6. Kementerian Kesehatan RI. Data Program Deteksi Dini Sadanis dan IVA. Jakarta: Kementerian Kesehatan: Subdit Penyakit Kanker dan Kelainan Darah; 2018.
7. Cardoso, Loibl, Pagani, Graziottin, Panizza, Martincich, et al. The European Society ofBreast Cancer Specialists Recommendations for the Management of Young Women with Breast Cancer. European Journal of Cancer.2012:48(2);3355-3377.
8. Azim HJ, Partridge A. Biology of Breast Cancer in Young Women. Breast Cancer Research. 2014:16(4);1-9.
9. Kementerian Kesehatan RI. Laporan Riset Penyakit Tidak Menular: Tumor Payudara dan Lesi Prakanker Serviks. Jakarta: Badan Penelitian dan Pengembangan Kesehatan;2016.
10. Castells X, Domingo L, Corominas J, Torá-Rocamora I, Quintana M, Baré M, et al. Breast Cancer Risk After Diagnosis by Screening Mammography of Nonproliferative or Proliferative Benign Breast Disease: A Study from A Population-based Screening Program. Breast Cancer Research and Treatment. 2015:149(1);237-244.
11. Murti B. Prinsip dan Metode Riset Epidemiologi. Yogyakarta: UGM; 1997.
12. Dewi GAT, Hendrati LY. Analisis Risiko Kanker Payudara Berdasar Riwayat Pemakaian Kontrasepsi Hormonal dan Usia Menarche. Jurnal Berkala Epidemiologi. 2015:3(1);12-23.
13. Nasution WM, Asfriyanti. The Analysis of Breast Cancer Causes at General Hospital Dr. Pringadi Medan. Advances in Health Sciences Research. 2017:9(2);43-47.
14. Bidgoli S, Eftekhari T. Role of Exogenous and Endogenous Sources of Estrogen on the Incidence of Breast Fibroadenoma: Casecontrol Study in Iran. Asian Pacific Journal Cancer Prevention. 2011:12(5);1289-1293.
15. Lambe M, Hsieh C, Trichopoulos D, Ekbom A, Pavia M, Adami H. Transient Increase in the Risk of Breast Cancer after Giving Birth. New England Journal of Medicine. 1994:331(1);5-9.
16. Sihombing M, Sapardin A. Faktor Risiko Tumor Payudara pada Perempuan Umur 25-65 Tahun di Lima Kelurahan Kecamatan Bogor Tengah. Indonesian Journal of Reproductive Health. 2014:5(3);175-184.
17. American Cancer Society. Breast Cancer Facts & Figure 2013-2014. Atlanta: American Cancer Society; 2014.
18. Anggraini M. Hubungan Antara Usia Saat Timbulnya Menarche dengan Usia Saat Terjadinya Menopause Wanita di Kecamatan Kartasura. Jurnal Unimus. 2008:5(1);203-209.
19. Pratiwi H, Sety L, Tina L. Analisis Faktor Risiko Kejadian Penyakit Fibroadenoma Mammae (FAM) di Rumah Sakit Umum Daerah Bahteramas Provinsi Sulawesi Tenggara Tahun 2017. Jurnal Ilmiah Mahasiswa Kesehatan Masyarakat. 2017:3(2);2-11.
20. Hinyard L, Schwartz T. Marital Status, Stage of Diagnosis, and Survival in Younger Women with Breast Cancer. Value in Health Journal. 2016:19(3): A169.
21. Kvikstad A, Vatten LJ. Cancer Risk and Prognosis in Norway: Comparing Women in Their First Marriage with Women Who Have Never Married. Journal of Epidemiology and Community Health. 1996:50(1);51-55.
22. Rianti E, Tirtawati GA, Novita H. Faktor-Faktor yang Berhubungan dengan Risiko Kanker Payudara Wanita. Journal Health Quality. 2012:3(1);10-23.
23. Russo J, Russo I. Breast Development, Hormones, and Cancer. Advances in Experimental Medicine and Biology. 2008:630;52-56.
Authors
Ahsani, R. F., & Machmud, P. B. (2019). Hubungan Riwayat Reproduksi dengan Tumor Payudara pada Perempuan Usia Muda di Indonesia (Analisis Riset PTM 2016). Media Kesehatan Masyarakat Indonesia, 15(3), 237-244. https://doi.org/10.30597/mkmi.v15i3.6278
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