Kendali Glikemik pada Pasien Diabetes Melitus Tipe 2 dengan dan tanpa Tuberkulosis Paru
Abstract
Glycemic control is important for people with diabetes mellitus (DM) because it has implications for effortsto manage DM. Pulmonary tuberculosis (PTB) is one of the many complications in DM patients associatedwith the process and results of treatment of the disease. The study aimed to determine glycemic control based onparameters of fasting blood glucose level (FBG), 2 hours post prandial blood glucose (2hPBG) and HbA1c in patientswith type 2 diabetes mellitus (T2DM) who had pulmonary TB. A cross-sectional study was conducted on 45T2DM subjects with PTB and 45 T2DM subjects without PTB who were outpatient in two hospitals in Surabaya.The results of the examination of FBG, 2hPBG, and HbA1c were analyzed descriptively, displayed in the form ofmean values and standard deviations (SD). The mean and SD were FBG (202.11 ± 78.68 mg/dl), 2hPBG (283.20± 107.20 mg/dl), and HbA1c (11.20 ± 2.61%) in T2DM subjects with pulmonary TB while subjects without pulmonaryTB were obtained FBG (175.29 ± 61.38 mg/dl), 2hPBG (208.22 ± 75.60 mg/dl), and HbA1c (9.34 ± 2.22%).The mean of FBG, 2hPBG and HbA1c of T2DM patients with pulmonary TB were higher than T2DM withoutpulmonary TB. This shows that the control criteria for DM that have not yet reached the target need to be done inan effort to better monitor glycemic control.
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2. Perkumpulan Endrokrinologi Indonesia. Konsensus Pengelolaan dan Pencegahan Diabetes Melitus Tipe 2 di Indonesia. Jakarta: PB. PERKENI; 2015.
3. IDF. Diabetes Atlas Sixth Edition, International Diabetes Federation. Brussels: http:/www.eatlas.idf.org; 2013.
4. Kementerian Kesehatan. Laporan Nasional Riset Kesehatan Dasar. Jakarta: Kementerian Kesehatan RI; 2013.
5. WHO. Global Tuberculosis Report 2015. WHO; 2015.
6. Esmail H, Barry C.E., Young D.B., & Wilkinson R.J, The Ongoing Challenge of Latent Tuberculosis. Phil.Trans.R.Soc. 2014;(369):1-14.
7. Kapur A, Harries A.D., Lonnroth K, Bygjerg C & Lefebvre P, Diabetes and Tuberculosis Old Associates Posing a Renewal Public Health Challenge. European Endrocinology;2009;12-14.
8. Kapur A & Harries A.D. The Double Burden of Diabetes and Tuberculosis - Public Health Implications. Diabetes Research and Clinical Practice. 2013;(101):10-19.
9. Wijayanto A, Burhan E., Nawas A., & Rochsismandoko, Faktor Terjadinya Tuberkulosis Paru pada Pasien Diabetes Melitus Tipe 2. J. Respir Indo. 2015;(35):1-11.
10. Fauziah DF, Basyar M & Manaf A. Insidensi Tuberkulosis Paru pada pasien Diabetes Melitus Tipe 2 di Ruang Rawat Inap Penyakit Dalam RSUP Dr. M. Djamil Padang. Jurnal Kesehatan Andalas. 2016;5(2):349-54.
11. Elorriaga G.G., & Pineda D.R., Type 2 Diabetes Mellitus as a Risk Factor for Tuberculosis. Mycobacterial Diseases Journal. 2014;(4):1-6.\
12. Cahyadi A., & Venty. Tuberkulosis Paru pada Pasien Diabetes Mellitus. J Indon Med Assoc. 2011;(61):174-78.
13. Zhao W, Shi L, Fonseca V.A, He J, Shao D, Zhao J, Chen Q & Yin A. Screening Patients with Type 2 Diabetes for Active Tuberculosis in Communities of China. Diabetes Care Journal. 2013;(36):159-160.
14. Lin Y.H.,, Chen C.P., Chen P.Y., Huang J.C., Ho C, Weng H.H., Tsai Y.H., & Peng Y.S., Screening for Pulmonary Tuberculosis in Type 2 Diabetes Elderly : a Cross-Sectional Study in a Community Hospital. BMC Public Health. 2015;(15):1-8.
15. Prakash B.C., Ravish K.S., Prabhakar B, Ranganath T.S., Naik B, Satyanarayana S, Isaakidis P. & Kumar A.M.V., Tuberculosis Diabetes Mellitus Bidirectional Screening at a Tertiary Care Centre, South India. Public Health Action. 2013;(3):18-21.
16. Boyilla N., & Madas S,. Relationship between Diabetes Mellitus and Pulmonary Tuberculosis and Outcome of Treatment. International Journal of Advances in Medicine. 2016;(3):504-08.
17. Kornfeld H, West K, Kane K, Kumpatla S, Zacharias R.R., Martinez-Bolzano C, Li W., & Viswanathan V. High Prevalence and Heterogeneity of Diabetes in Patients with TB in South India. Journal.publication.chesnet.org. 2016;1501-08.
18. Das S, Das E,Bhuyan K, Prusty B, Barik M, Yadav VS & Hussain T., Biderectional Screening of Tuberculosis Patients for Type 2 Diabetes and Diabetes Patients for Tuberculosis in Bhubaneswar, Odisha. International Journal of Community Medicine and Public Health. 2017;4(7):2435-42.
19. Fwoloshi S, Hachaambwa L.M., Chiyenu K.O., Chirwa L, Hoffman T.W., Ngalamika O & Bailey S.L,. Screening for Diabetes Mellitus among Tuberculosis Patients: Finding from a Study at a Tertiary Hospital in Lusaka, Zambia. Canadian Journal of Infectious Disease and Medical Microbiology. 2018;1-5.
20. Wulandari D.R., & Yani J.G., Diabetes Melitus dan Permasalahannya pada Infeksi Tuberkulosis. .J Respir Indo. 2013;(33):126-34.
21. Ahmed M, Omer I, Osman S.M., & Ahmed-Abakur E.H., Association between Pulmonary Tuberculosis and Type 2 Diabetes in Sudanese Patients. The International Journal of Microbiology. 2017; (6): 97-101.
22. Bokam B.R., & Thota P,. Effect of Glycemic Control of Pulmonary Tuberculosis in Diabetics. India Journal of Basic and Applied Medical research. 2016;(5):198-207.
23. Chiang C.Y., Bai K.J., Lin H.H., Chien S.T., Lee J.J., Enarson D.A., Lee T.I., & Yu M.C. The Influence of Diabetes, Glycemic Control, and Diabetes-Related Comorbidities on Pulmonary Tuberculosis. Journal.pone.2015;1-15.
24. Lee P.H., Fu H, Lai T.C., Chiang C.Y., Chan C.C., & Lin H.H., Glycemic Control and the Risk of Tuberculosis : A Cohort Study. Journal PLOS Medicine. 2016;1-15.
25. Hou X.H., Wang C, Wang S, Yang W, Ma Z, Wang Y, Li C, Li M, Zhang X, Zhao X, Sun Y, Song J, Lin P, Liang K, Gong L, Wang M, Liu F, Li W, Yan F, Yang J, Wang L, Tian M, Liu J, Zhao R, Chen S & Chen L. Fluctuation between Fasting and 2-H Postload Glucose State is Associated with Glomerular Hyperfiltration in Newly Diagnosed DiabetesPatients with HbA1c <7%. Journal PLOS ONE. 2014;(9):1-7.
Authors
Wahiduddin, W., Pranoto, A., & Sudjarwo, S. (2019). Kendali Glikemik pada Pasien Diabetes Melitus Tipe 2 dengan dan tanpa Tuberkulosis Paru. Media Kesehatan Masyarakat Indonesia, 15(1), 99-109. https://doi.org/10.30597/mkmi.v15i1.5292
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